adminipi

The medicine of the future against infection and inflammation?

Aug 21, 2018

Researchers at Lund University in Sweden, have in collaboration with colleagues in Copenhagen and Singapore, mapped how the body’s own peptides act to reduce infection and inflammation by deactivating the toxic substances formed in the process. The study is published in Nature Communications and the researchers believe their discovery could lead to new drugs against infection and inflammation, for example in wound healing. The toxins that are neutralised, known as lipopolysaccharides (LPS), come from the bacterial cell walls and generate an inflammatory reaction. The reaction is a necessary part of our immune defence system in which our bodies respond quickly ...

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US nod for Opdivo in pre-treated small cell lung cancer

Aug 21, 2018

US regulators have further expanded the scope of Bristol Myers Squibb’s Opdivo, approving its use for a previously treated small cell lung cancer. The immunotherapy is now the first and only immuno-oncology treatment option for patients with metastatic small cell lung cancer (SCLC) whose cancer has progressed after platinum-based chemotherapy and at least one other line of therapy. Clearance for this indication was granted by the US Food and Drug Administration under the regulator’s accelerated approval pathway based on overall response rate (ORR) and duration of response (DOR) data, so continued approval may be contingent upon verification of clinical benefit ...

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Trump urges Justice Department to target opioid makers with a ‘major lawsuit’

Aug 21, 2018

Months ago, the Department of Justice backed the hundreds of lawsuits that accuse drugmakers and distributors of their alleged contribution to the nation’s opioid epidemic. Now, President Donald Trump is asking Attorney General Jeff Sessions to take another step, to bring “a major lawsuit” of its own. During a cabinet meeting on Thursday, Trump asked Sessions to bring “a major lawsuit” against opioid makers “that are really sending opioids at a level that it shouldn’t be happening,” according to a conference transcript from the White House. Trump said that instead of joining existing litigation brought against the companies, he wanted ...

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EU patients may miss out on medicines in no-deal Brexit, says AstraZeneca

Aug 21, 2018

Pharmaceutical giant AstraZeneca has said patients in the European Union may not be able to receive vital medicines from the UK if the company does not successfully prepare for a no-deal Brexit. The manufacturer of cancer, heart and lung drugs told an official Dutch government website that it was going to have to test medicines in both the UK and the EU to ensure they could cross the border in all Brexit scenarios. But AstraZeneca conceded that it could not guarantee it would succeed, and emphasised that in its case it could be EU citizens who will be at risk, ...

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Innovative New Platform to Revolutionise Environmental Monitoring

Aug 21, 2018

Hanwell Solutions Ltd, the UK’s leading manufacturer of wireless environmental monitoring solutions, has launched a new, state of the art software platform that will revolutionise access to real-time data and reporting capabilities for pharmaceutical and healthcare companies any time, anywhere, across the world. Hanwell EMS has been specially developed by the British manufacturer’s specialist software engineers to interface seamlessly with Hanwell Pro and Hanwell IceSpy monitoring solutions in an industry-leading hardware/software combination. The browser-based user interface is easy to navigate and the single platform incorporates interactive tools for analysis and immediate alarm notification. Hanwell EMS is perfect for smaller applications ...

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