Simplified Bioprocess Setup through Automated Process Control

Apr 11, 2017

Learning to use a bioprocess controller is a complex and often intimidating endeavor for the beginner. Indeed, even with previous bioprocess experience, moving to a new software platform can entail much learning and reduce efficiency. Although many textbooks and manuals exist on the subject, they are no substitute for hands-on experience. Ulrike Becken and her team at Eppendorf AG Bioprocess Center explain how automated process control can help users who are less familiar with bioreactors and fermenters. ...

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Antimicrobial Copper vs Antimicrobial Resistance

Apr 11, 2017

The antimicrobial properties of copper have become widely known, harnessed by hospitals around the world in the form of touch surfaces that continuously reduce bioburden. Now, a potential role in combatting antimicrobial resistance is being proposed by researchers. In his article, Bryony Samuel at Copper Development Association describes some of the latest developments in antimicrobial copper, looking at new science, its growing inclusion in guidelines and ratings systems, and a high-profile installation at a leading London research facility. ...

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Reducing Particulate from Metal Products in Medical Devices

Jan 8, 2016

As the medical device market evolves to become highly sophisticated and advanced, metal part manufacturers face constant pressures in being able to reduce particulate in the production and assembly of components. For medical device component manufacturers, developing new methods to reduce particulate is becoming increasingly important. Graham Perkins, Medical Sales Manager at Advanex, discusses the reduction of particulate from metal products in medical devices. ...

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A Quality-by-design Approach to Upstream Bioprocess Interrogation and Intensification

Jan 7, 2016

Efficient biopharmaceutical process development relies on the quality-by-design (QbD) paradigm. QbD is a scientific, risk-based proactive approach to drug development that aims to have a full understanding of how the process and product are related. This knowledge is gained by process analytical technology (PAT). Stephen Craven and Ulrike Becken at Eppendorf deal with upstream bioprocess interrogation and intensification. ...

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Formulation for Improved Liquid Biotherapeutics

Oct 17, 2013

Many biotherapeutic drug products are prepared as lyophilised powders, but there is a growth in the number being formulated as liquid presentations for prefilled syringes. Nicholas Darton at Arecor Ltd explains how this move towards prefilled syringes is driven by the user-friendly and cost-effective attributes of these devices. ...

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