Emerging Treatment, Peptide Receptor Radionuclide Therapy, Provides New Treatment Option for Gastroenteropancreatic Neuroendocrine Tumours

Apr 12, 2018

With nuclear medicine therapeutics expected to represent 60% of the projected $26 billion global molecular nuclear medicine market by 2030, new alternative treatments are now beginning to emerge for conditions including gastroenteropancreatic neuroendocrine tumours (GEP-NETs). Of these nuclear medicine innovations, peptide receptor radionuclide therapy (PRRT) is an option that combines the advantages of two of the most successful approaches to cancer treatment: external beam radiation and tumour targeted therapy. This article by Stefano Buono and Rachel Levine of Advanced Accelerator Applications explores this treatment. ...

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An Update on Pulmonary Drug Delivery of Dry Powders

Apr 12, 2018

Inhalation of air is a vital process for all human life. Inhalation for drug delivery has been established as an effective delivery method of active pharmaceutical ingredients to a human body, mostly in the field of anesthesia and respiratory diseases. In this article, the status and new trends in the field of drug delivery to the lungs will be reviewed by Rachel van Rijn and Harry Peters of DFE Pharma, with focus on the delivery of active pharmaceutical ingredients (APIs) in the form of dry powders. ...

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MALDI Imaging at High Speed

Apr 12, 2018

Over the last decades, MALDI-TOF mass spectrometry (Matrix-Assisted Laser Desorption/Ionisation Time of Flight) has proven its usefulness and robustness in many applications, helping life scientists to meet their toughest challenges. This article by Rohan Thakur of Bruker Daltonics will focus on how new laser technology can improve sample throughput for MALDI imaging. It will demonstrate how MALDI technology is being utilised in drug development as an established tool for compound distribution analysis and an emerging tool to boost efficiency in the drug finding process, specifically for ultra high-throughput drug discovery screening. ...

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Key Challenges of Bringing New Drug Delivery Devices to Market

Apr 12, 2018

There are many challenges in bringing a good new product to market, from correctly identifying the right commercial opportunity and establishing appropriate input requirements, to developing and industrialising a product which is appealing, usable and robust. There are myriad development tools, techniques, processes and best practices that multi-disciplinary teams can employ to tackle these challenges. Chris Hurlstone, Team Consulting’s Director of Engineering, gives an account of what these challenges are, and how they can be overcome. ...

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Successful Adoption of eConsent Best Practices for Integrating eConsent Technology

Apr 12, 2018

Research sponsors and investigative sites are continuing to explore the use of electronic informed consent (eConsent) in today’s clinical trials. eConsent utilises electronic systems and processes, such as audio and video features, to communicate study information to study participants to securely obtain and document informed consent. In a time when the clinical trials industry is seeing an influx of technology across the clinical trials lifecycle, Mika Lindroos of CRF Health explains why there is a need to move towards consolidating these technologies and bringing complementary platforms together wherever possible. ...

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