Better Together – Achieving Collaborative Compliance

Dec 17, 2018

When it comes to achieving supply chain flexibility and consistency, adopting a collaborative, compliant approach goes a long way in the protection of transporting pharma payloads worldwide. Ira Smith at Pelican BioThermal discusses how the healthcare industry is seeing the emergence of more cohesive, cooperative partnerships between the temperature-controlled packaging (TCP) manufacturers, pharmaceutical companies, freight forwarders and logistics companies in a bid to secure stability and flexibility in the pharma supply chain. ...

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Airfreight Still Poses Major Obstacles for Temperature Sensitive Pharma Logistics

Dec 17, 2018

A staggering 35 billion US$ (31 billion €) per year are lost in the pharmaceutical industry due to temperature excursions. With its CEIV Pharma certification, the international airline association IATA is trying to set standards and spread best practices, as booming pharma destinations such as ASEAN and Africa are still lagging behind in infrastructure and training to handle temperature-sensitive pharmaceuticals. Thomas Rheinfeld, a Technology Writer and Business Analyst, argues that even in the developed world, airfreight still faces enormous challenges. ...

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Sticky Situation: How to Avoid Sticking and Picking

Dec 17, 2018

Sticking and picking problems are ubiquitous in tablet manufacturing. In the regulated world of drug-product manufacturing, there is often a sense of urgency to develop a new molecule. But this urgency can result in hasty decisions to enter clinical trials or submit for regulatory approval with a formulation that ultimately results in unanticipated compression scale-up problems, discusses Jonathan Gaik at Natoli Scientific. ...

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Keep it Dry: Roller Compaction

Dec 17, 2018

David O’Connell at PCI Pharma Services discusses the advantages and general principles of dry granulation roller compaction as an alternative to traditional wet granulation manufacturing – particularly in the development and manufacturing of solid oral dosage forms, including tablets and capsules containing highly potent active pharmaceutical ingredients (API). ...

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Dissolving Solubility Challenges

Dec 17, 2018

In this article, Kimberly Zubris at CDMO Particle Sciences explores the latest trends in formulation development of insoluble compounds, techniques to improve bioavailability and why a data-driven approach should be taken to address individual compound needs. ...

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