Discovery Toxicology Services

Jan 7, 2014

Toxicology the study of poisons, determines whether a drug can be used on humans. Almost 30% of clinical trial attritions are attributed to the toxicological profile of a molecule. The patent cliff’s drying pipelines are driving the fail early and are failing safe practices in the drug development process. Meenakshi L at Beroe Inc., provides an overview of discovery toxicology and how this is being outsourced by the large pharma in bits and pieces owing to lack of efficiency in-house. ...

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Improving and Refining Models of Acquired Resistance for Efficient Oncology Drug Discovery

Jan 7, 2014

Conventional chemotherapy has been, for many years, the prevalent type of anti-cancer treatment. However its broad-based mechanisms, DNA alkylating agents, usually lead to severe systemic side effects.  Dr. Rajendra Kumari at Precos Ltd, looks into how today the treatments inhibiting specific molecules that have a role in tumour growth or progression have become successful.  http://ipimediaworld.com/wp-content/uploads/2014/01/Improving….pdf ...

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