How can Pharma Develop Paedriatic Medicine?

Feb 11, 2015

In the evolving healthcare landscape, the key of patient engagement, education and empowerment are only just starting to be scrutinised in paediatric medicine. Dr Kate Hersob, UK CEO and Co-Founder of Medikidz discusses the many as-yet unexplored opportunities for the pharmaceutical industry to become established leaders in driving innovation in these areas. With a history of industry is ideally placed to support healthcare professionals with new initiatives to provide engaging and appropriate educational tool for use with young patients. ...

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Impact of Sterilisation Method on Packaging Component Machinability Performance: Steam vs. Gamma Evaluation of the 1ml Long Plunger

Oct 1, 2014

The machinability of parenteral packaging components is recognised to have a significant influence on productivity of the drug product manufacturing process. As Simon Côté of West Pharmaceutical Services explains, there are various processes that can be used for washing and sterilising elastomers for aseptic fill, and depending on conditions of processing, the physical and functional characteristics of the component will be altered to some degree. In this case study, elastomeric components intended for aseptic processing are considered with respect to machinability on a lab-scale filling line. ...

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Gentlewing: The Name Says It All

Oct 1, 2014

Implementing innovations in the pharmaceutical market is an ambitious task. In an industry that requires precise and reproducible results, changes to current systems always involve certain challenges. According to Dr Marcus Knöll of Bosch, an external study can provide certainty, which was the case with the uniquely shaped ‘Gentlewing’ mixing device from Hüttlin GmbH, a subsidiary of Bosch Packaging Technology, based in Schopfheim, Germany. A study conducted by the University of Mainz, Germany, confirmed that the special design of the device offers several advantages to users – while achieving the same processing results as a conventional mixer. ...

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Small Changes to Tablet Shape Bring Big Results

Oct 1, 2014

Tablet shape is generally given the most consideration as new products are branded by marketing departments, whereas whole campaigns have been built around a tablet’s colour or shape. Dale Natoli of Natoli discusses the importance of considering the potential of small adjustments to tablet shape to influence everything from production efficiency to consumer acceptance. An improper tablet design can cost millions in lost production and possibly lead to a disastrous product launch. ...

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When Two is Better than One: The Benefits of Two-Floor Production Facilities for Future-Proof Manufacturing Capability

Oct 1, 2014

The impact of batch transfer methods on the ‘Lean success’ of a plant is starting to be recognised earlier in the plant design process. Before deciding on building and process room heights, proper attention must be given to materials handling processes. A single-floor facility design is simply not flexible enough, and a multiple-floor plant could well be too expensive. A two-floor facility is a good compromise as it provides good agility for future demands with a modest investment requirement. Wim Spook of Matcon looks into the pros and cons of these different facility designs, exploring the benefits to the future ...

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