Advocating an Integrated Approach to the Global Diabetes Epidemic

Dec 17, 2014

The non-communicable disease of diabetes has reached epidemic proportions, and it knows no geographic boundaries. It`s time to take a sombre look at the consequences of letting the worldwide diabetes epidemic continue to progress, and decide how we, as a globally unified body of health professionals and health agencies, wish to proceed, points out Dr J. Rick Turner of Quintiles. He advocates for the adoption of an integrated approach to addressing the global diabetes epidemic, because it offers the most promise for the prevention of future cases of diabetes, and for the treatment of patients who currently have diabetes. ...

Read More

Opportunities for Monoclonal Antibodies in Bacterial Infectious Diseases

Dec 17, 2014

The management of infectious disease is challenged by trends that impact patient welfare on a global scale; the emergence of multi-drug-resistant (MDR) forms of new and old bacterial pathogens, the world’s increasing population of immunocompromised patients where antimicrobial therapy is less effective, and fewer new antibiotics being licensed. If these trends continue, the dreaded “post-antibiotic era” could become a reality. Fraser Leslie of Arsanis discusses the vast potential of monoclonals for combating antibiotic resistance with many anti-infectious mAbs currently in development. ...

Read More

Revisited Cell Cultures and Valuable Methods for Pre-clinical Studies

Dec 17, 2014

During the last ten years, the development of transgenic techniques has rendered possible the creation of mutant strains of rodents mimicking human diseases and the assessment of the role of biochemical lesions in their development. However, maintaining and expanding colonies of transgenic rodents is time-consuming, expensive and above all, the characterisation (phenotyping) of these new animals needs highly experienced people. Pr. Philippe Poindron of Neuro-Sys looks into the development of alternative methods for studying efficiency and mode of action of new compounds in preliminary preclinical studies. ...

Read More