Horizon Discovery enters into agreement with Roche Diagnostics to support the development of immunohistochemistry assays for oncology

Dec 19, 2017

Horizon Discovery Group plc, a global leader in gene editing and gene modulation technologies, today announces that it has entered into an agreement with Roche Diagnostics to assist in the development of immunohistochemistry (IHC) assays.   Under the terms of the agreement, Horizon will develop and provide Reference Standard material expressing neurotrophic tropomyosin receptor kinase (NTRK) fusion biomarkers. NTRK gene rearrangements have recently emerged as promising targets for cancer therapy, and a number of novel compounds have been developed against the fusion proteins that arise from these molecular alterations. Their effective application, however, depends upon the accurate determination of the ...

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With UK Pharma facing Brexit headwinds, could UK Gov’t defeat help industry by leading to a “softer” Brexit? asks GlobalData

Dec 19, 2017

The UK Government’s narrow defeat (Wednesday 13th November) on amendment seven of the European Union withdrawal bill, demanding that Parliament have a binding vote on the final Brexit deal, has fuelled a debate on whether the UK could now be heading for a softer Brexit and what impact this will have on leading industries like UK pharma. A recent webinar by GlobalData, a leading data and analytics company, brought together industry leaders* to review the reputational, economic and R&D implications of Brexit for the UK pharma sector. Reputational From a reputational point of view, the UK’s status as a first-tier ...

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Major changes for bio supply forecast in 2018 by bioLIVE

Dec 19, 2017

Industry experts from bioLIVE – the new UBM biomanufacturing and bioprocessing event taking place next year in Madrid (October 9-11) – predict that 2018 will usher in a new age of increased integration and collaboration across the large and small molecule supply chain. Additionally, next year will also see a continued rise in the European bioprocessing and biomanufacturing sectors, along with a resurgence in European biotechs. Experts at UBM have been studying market developments ahead of the new event’s launch, and one of the key factors identified is the relative states of maturity of the supply chains. The small molecule ...

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Cresset: innovative science and intuitive software

Dec 19, 2017

Chemists from the world’s leading research organizations trust Cresset to help them understand the key chemical interactions that underpin biological activity. We provide software and services to 8 out of the top 10 pharmaceutical companies.   Save time and money using our in silico methods to identify the molecules that matter to your project. Discover, design and optimize the best small molecules with:   Unrivalled insight into your protein-ligand systems Outstanding visualization and multi-parameter optimization tools Biologically relevant searches of millions of compounds.   Cresset software suite comprises:   Flare: Outstanding new methods for your protein-ligand system Forge: Ligand-focused suite for ...

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