Business Partnering – The Way Forward for Cryogenics

Apr 28, 2012

The essential background of technology is being masterminded by specialists in the exacting science of cryogenics. Patrick Jackson, a qualified engineer at Vindon Scientific, explores how technology is often reliant on the expertise of one or more partners joining forces to improve overall resources. ...

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Determination of Efficacy of AnvirzelTM in 37 Established Cancer Cell Lines

Apr 28, 2012

Maria Toloudi, Marina Chatziioannou and Loannis Papasotiriou, of Research Genetic Cancer Centre Ltd, investigate the efficacy of Anvirzel™, an extract of Nerium oleander, in more than 35 different human cancer cell lines, including all types of tumours, and how the drug has a wider field of action in other cancer cell lines. ...

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Implementing Personalised Medicine in clinical settings

Apr 28, 2012

Dr James Sawyer, CEO of Prism Ideas, explores the effect of the completion of the human genome project in 2003, and how the field of personalised medicine has been advancing at a fast pace, with scientists and clinicians gaining critical insight into the biology of numerous medical conditions. This knowledge, combined with the long-known fact that risk of disease and response to treatment varies from person to person, has enabled the development of personalised medicine, with oncology being one of the fields reaping the greatest benefits. ...

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Antimicrobial Peptides: Therapeutic Potential

Apr 28, 2012

Bacterial resistance to traditional antibiotics over the last twenty years has reached unprecedented heights. For the first time since the discovery of penicillin, some bacterial infections such as MRSA can be considered untreatable. Other major pathogen species are displaying similar increases, which is causing considerable concern. Such a worrying scenario has fuelled the search for alternative antimicrobials. One such option is the development of cationic antimicrobial peptides (CAPs). John T George, D Rowley and R Zheng of University of East London (UEL) review the challenges that this class of antimicrobials face in order to become viable alternatives to the traditional ...

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Painful Transition from Paper to Electronic Submission Dossiers

Apr 28, 2012

For many years, submissions have been prepared in accordance with the specific national requirements of the countries where the medicinal products are to be marketed. Increasing co-operation among the regulatory authorities, spurred on by initiatives such as ICH, have looked at ways of reducing time-consuming reworking of data for each region and focused on producing a harmonised set of requirements. Tim Felgate, Regulatory Intelligence Consultant at Applied Regulatory Consulting Ltd portrays the sometimes painful transition from paper to electronic submission dossiers, and the potential future trends. ...

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