Drug Delivery: Thin Dissolving Films Begin to Come of Age

Mar 12, 2012

Thin Dissolving Films have been in use for industrial applications for over 25 years. The first real public awareness of edible thin films was the high-profile launch of Listerine Breath Fresheners, which spawned many copycat products. Consumers decided these were imitation rather than innovation, and growth of this new technology stalled. Chris Hatton, Business Development Director at BioFilm Ltd, explains how, with the success of Suboxone Film, a unique thin film application of a controlled drug ensuring increased patient compliance; TDF technology is once again being taken seriously for pharmaceutical and consumer healthcare products. ...

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Supply Chain Management. It’s More than Just Freight

Mar 12, 2012

Effective supply chain management requires more than the ability to transport freight from A to B. It starts with procurement and involves packing, insurance, customs regulations and controlling a range of risks along the way. Lucy Jenner, Marketing Manager at Charles Kendall explains why involvement in major government programmes or niche commercial contracts makes effective management of supply chains by air, sea, rail or road vital to controlling costs and maximising profit in any business. ...

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Applying Multi-Parameter Optimisation in Drug Discovery: Explore Broadly but Focus Quickly on High Quality Compounds

Mar 12, 2012

Finding a successful drug is a delicate balancing act. It is necessary to simultaneously optimise many, often conflicting, requirements to identify a compound that will ultimately become a safe and efficacious drug. Methods for guiding this process, commonly referred to as multi-parameter optimisation (MPO) have been developed. Matthew Segall, Director and Ceo at Optibrium explores how these can be applied in practice to improve productivity and efficiency in drug discovery. ...

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Early PK-PD Modelling Significantly Facilitates Identification of the Best Drug Candidates

Mar 12, 2012

Pharmacokinetics and pharmacodynamics are disciplines that can straddle discovery and development when considered in their complex physiologic relationship to one another using a sophisticated PK/PD model. Richard Slauter, Senior Director of Drug Metabolism/Pharmacokinetics and Senior Principal Study Director at MPI Research, describes how traditionally pharmacokinetics is placed in the preclinical discovery phase, because it is a series of studies that helps to narrow the number of molecules being evaluated for a particular therapeutic approach. ...

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FlandersBio, Building Biotech Bridges

Mar 12, 2012

FlandersBio is the umbrella organization for the life sciences and biotechnology sector in Flanders. This network brings together companies with innovative, R&D-driven activities in the life sciences sectors. Joke Comijn, Communications Manager at FlandersBio, provides an overview of Knowledge for Growth and an insight into Europe’s largest regional biotech convention. ...

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