The human heart is one of nature’s engineering marvels, considering the requirement specifications for this fist-sized hollow organ that only weighs 250–300 grams. Delivering about five litres of blood at an average of 75 contractions per minute, it is required to perform without interruption. Considering the high performance demands, failings can occur beyond normal wear and tear in the heart’s electrical system, the valves, and the muscle itself. Of all complications leading to heart disease, ischemia – the insufficient supply of oxygen caused by restricted blood supply to the cardiac muscle – is the most prevalent. Dr Roman Schenk of Recardio explores the possible solutionsto this issue.